Description

-Fluoro-2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value organoboron building block, specifically a pyridine boronic ester, essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a pivotal method for constructing complex molecules with precision. This compound is critically needed by R&D and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in drug discovery for fluorinated and heterocyclic compounds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl and heterobiaryl linkages.
• Chemical Biology Probes: Serves as a precursor for labeled compounds and molecular probes used in biochemical research.
• Ligand Synthesis: Acts as a starting material for preparing complex ligands used in catalysis and coordination chemistry.

Basic Information

Item	Details
Product Name	-Fluoro-2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1220696-64-9
Molecular Formula	C13H19BFNO2
Molecular Weight	251.11 g/mol
Synonyms	2-Fluoro-6-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluoro-6-picoline; 2-Fluoro-6-methylpyridine-3-boronic acid pinacol ester; 3-Boronic acid, 2-fluoro-6-methyl-, pinacol ester; (2-Fluoro-6-methylpyridin-3-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our -Fluoro-2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 19F, 11B), and GC/MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.