Description

Ccr1 Inhibitor 19E is a potent and selective small molecule antagonist of the C-C chemokine receptor type 1 (CCR1), a key target in inflammatory and autoimmune disease pathways. This high-purity compound is essential for pharmaceutical R&D, enabling critical studies in drug discovery and mechanism validation. It is primarily utilized by researchers and developers in the biotechnology and pharmaceutical industries for preclinical investigation and assay development.

Application

• Drug Discovery Research: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anti-inflammatory therapeutics.
• In Vitro & In Vivo Pharmacology: Enables the study of CCR1-mediated signaling pathways in cellular assays and animal models of autoimmune diseases.
• Biochemical Assay Development: Serves as a key tool compound for high-throughput screening (HTS) and binding affinity studies to identify new CCR1 inhibitors.
• Mechanism of Action (MoA) Studies: Critical for validating the role of CCR1 in specific disease pathologies, such as rheumatoid arthritis, multiple sclerosis, and transplant rejection.
• Academic & Contract Research: Supports fundamental research in immunology and inflammation at universities and contract research organizations (CROs).

Basic Information

Product Name	Ccr1 Inhibitor 19E
CAS No.	1220026-26-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CCR1 Inhibitor 19E; 19E, Ccr1 Inhibitor; CCR1 antagonist 19E; 1220026-26-5; (S)-2-(4-Chlorophenyl)-1-(4-((4-fluorobenzyl)oxy)phenyl)-N-(1-phenylethyl)-1H-imidazole-5-carboxamide; BMS-817399; BMS 817399
EINECS	Contact for details

Quality Control

Our Ccr1 Inhibitor 19E is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.