Description

(+/-)-Ibuprofen-D3 Sodium Salt CAS NO 1219805-09-0 is a high-purity, deuterium-labeled internal standard of ibuprofen sodium, essential for ensuring analytical accuracy and reliability in quantitative mass spectrometry. This stable isotope-labeled compound is critical for applications requiring precise measurement and compensation for matrix effects or analyte loss. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in bioanalytical method development, pharmacokinetic studies, and drug metabolism research.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a quantitative reference standard in the bioanalysis of ibuprofen and its metabolites in biological matrices (plasma, serum, urine).
• Pharmacokinetic and Bioequivalence Studies: Enables accurate measurement of drug concentration-time profiles for clinical and pre-clinical research.
• Drug Metabolism and Disposition (DMPK) Research: Facilitates the study of metabolic pathways and the quantification of parent drug and metabolites.
• Method Development and Validation: Serves as a critical component in developing and validating robust, GLP-compliant analytical methods.
• Quality Control in Pharmaceutical Manufacturing: Can be utilized in impurity profiling and assay verification of ibuprofen-based drug products.
• Forensic and Anti-Doping Analysis: Supports accurate quantification in specialized testing scenarios requiring high specificity and sensitivity.

Basic Information

Product Name	(+/-)-Ibuprofen-D3 Sodium Salt
CAS No.	1219805-09-0
Molecular Formula	C13H15D3NaO2
Molecular Weight	232.29 g/mol (approx.)
Synonyms	Ibuprofen-d3 Sodium Salt; Sodium 2-(4-isobutylphenyl)propionate-d3; (±)-Ibuprofen-d3 Sodium Salt; DL-Ibuprofen-d3 Sodium Salt; Ibuprofen (phenyl-d3) Sodium Salt; Ibuprofen (methyl-d3) Sodium Salt; Ibuprofen Sodium Salt-d3; IBP-d3 Sodium Salt
EINECS	Contact for details

Quality Control

Our (+/-)-Ibuprofen-D3 Sodium Salt is manufactured under strict quality controls to ensure high chemical and isotopic purity suitable for sensitive analytical applications. Each batch is accompanied by comprehensive analytical documentation, including Certificates of Analysis (COA) detailing results for assay, isotopic enrichment, and purity by HPLC and NMR. We support compliance with relevant pharmacopeial standards and Good Laboratory Practice (GLP) requirements for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.