Description

Methyl 5-Chloro-2-Methoxy-D3-Benzoate is a high-purity, deuterium-labeled aromatic ester, a critical building block for advanced research and development. This compound is specifically valued for its isotopic labeling, which is essential for creating internal standards in mass spectrometry and for conducting detailed metabolic and pharmacokinetic studies. It is primarily required by pharmaceutical R&D laboratories, analytical chemistry service providers, and manufacturers of diagnostic reagents who demand precise and reliable chemical tools.

Application

• Internal Standard for LC-MS/MS: Serves as a stable, isotopically labeled internal standard for the accurate quantification of pharmaceutical compounds and their metabolites in complex biological matrices.
• Pharmaceutical Research: Used as a key deuterated intermediate in the synthesis of novel drug candidates, particularly in the development of anti-inflammatory and central nervous system (CNS) agents.
• Metabolite Identification: Employed in drug metabolism and pharmacokinetics (DMPK) studies to trace and identify metabolic pathways and degradation products.
• Analytical Reference Standard: Provides a certified reference material for method development, validation, and quality control in analytical laboratories.
• Isotope Labeling Studies: Facilitates mechanistic studies in organic chemistry and biochemistry where tracking molecular fate is necessary.

Basic Information

Product Name	Methyl 5-Chloro-2-Methoxy-D3-Benzoate
CAS No.	1219803-33-4
Molecular Formula	C9H6D3ClO3
Molecular Weight	203.64 g/mol
Synonyms	Methyl 5-chloro-2-(methoxy-d3)benzoate; Benzoic acid, 5-chloro-2-methoxy-d3-, methyl ester; 5-Chloro-2-methoxy-d3-benzoic acid methyl ester; Deuterated Methyl 5-Chloro-2-Methoxybenzoate; d3-Methyl 5-Chloro-2-Methoxybenzoate; Methyl 5-Chloro-2-(trideuteromethoxy)benzoate; (5-Chloro-2-methoxy-d3-phenyl)carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-2-Methoxy-D3-Benzoate is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.