Description

N,n-Dimethyl-D3-Chloroacetamide is a deuterium-labeled analog of N,N-Dimethylchloroacetamide, a versatile chemical intermediate. This isotopically labeled compound is critical for applications requiring precise tracking and analysis, such as in metabolic and pharmacokinetic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing and testing new compounds.

Application

• Pharmaceutical Research & Development: Serves as a deuterated building block in the synthesis of isotopically labeled active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Analytical Chemistry: Used as an internal standard in mass spectrometry (MS), liquid chromatography-mass spectrometry (LC-MS), and nuclear magnetic resonance (NMR) spectroscopy for accurate quantitative analysis.
• Agrochemical Development: Employed in the synthesis of novel, labeled pesticide and herbicide candidates to study environmental fate, degradation pathways, and residue analysis.
• Organic Synthesis: Acts as a key intermediate for introducing the -COCH2Cl moiety in labeled complex molecules for various research applications.
• Material Science: Potential use in the development of specialty polymers and advanced materials where deuterium labeling is required for structural or property analysis.

Basic Information

Product Name	N,n-Dimethyl-D3-Chloroacetamide
CAS No.	1219802-19-3
Molecular Formula	C4H5D3ClNO
Molecular Weight	136.59 g/mol
Synonyms	N,N-Dimethylchloroacetamide-d3; Chloro-N,N-dimethylacetamide-d3; Deuterated N,N-Dimethylchloroacetamide; (Chloroacetyl-d3)dimethylamine; 2-Chloro-N,N-dimethylacetamide-d3; N,N-Dimethyl-2-chloroacetamide-d3; CD3C(O)ClN(CH3)2; N,N-Dimethylchloroacetamide (D3 labeled)
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-D3-Chloroacetamide is produced under strict quality management systems to ensure high isotopic and chemical purity, essential for research integrity. Each batch is characterized by NMR, HPLC, and MS to confirm deuterium incorporation and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.