Description

Phenelzine-D5 Sulfate is a deuterated analog of the monoamine oxidase inhibitor (MAOI) phenelzine sulfate, specifically labeled with five deuterium atoms. This stable isotope-labeled compound is a critical reference material for ensuring accurate and reliable analytical results in quantitative mass spectrometry. It is primarily required by pharmaceutical research and development laboratories, clinical research organizations, and forensic toxicology facilities for use as an internal standard in LC-MS/MS and GC-MS methods.

Application

• Internal Standard for Bioanalysis: Essential for the precise quantification of phenelzine and its metabolites in complex biological matrices such as plasma, serum, and urine.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion in preclinical and clinical trials.
• Therapeutic Drug Monitoring (TDM): Supports the development and validation of robust assays to monitor drug concentrations in patients undergoing MAOI therapy.
• Metabolite Identification and Profiling: Aids in the structural elucidation and quantification of drug metabolites during drug development stages.
• Forensic and Clinical Toxicology: Used in confirmatory testing and method development for the detection of phenelzine in forensic casework or overdose scenarios.
• Method Development and Validation: Serves as a critical component for establishing FDA/EMA-compliant bioanalytical methods with high specificity and accuracy.

Basic Information

Product Name	Phenelzine-D5 Sulfate
CAS No.	1219798-40-9
Molecular Formula	C8H6D5N2 • H2SO4
Molecular Weight	Contact for details
Synonyms	Phenelzine-d5 sulfate; (2-Phenylethyl)hydrazine-d5 sulfate; Nardil-d5 sulfate; Phenelzine (phenyl-d5) sulfate; 2-Phenylethylhydrazine-d5 sulfate; β-Phenylethylhydrazine-d5 sulfate; MAOI-d5 internal standard; Deuterated phenelzine sulfate
EINECS	Contact for details

Quality Control

Every batch of Phenelzine-D5 Sulfate is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) that detail isotopic purity (D-enrichment), chemical purity (by HPLC), and identity confirmation (by NMR and MS). Our products are suitable for use in GLP/GMP-regulated environments, and we ensure traceability and consistency for critical research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is hygroscopic (moisture-sensitive); desiccants are recommended for long-term storage. Keep the container sealed under an inert atmosphere if possible to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.