Description

Oseltamivir Acid-D3 CAS NO 1219172-31-2 is a deuterium-labeled analog of the active metabolite of the antiviral prodrug Oseltamivir Phosphate. This stable isotope-labeled compound is a critical reference standard and intermediate in pharmaceutical research and development. It is primarily utilized by analytical chemists and researchers in the pharmaceutical and biotechnology sectors for method development, pharmacokinetic studies, and quantitative analysis.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a crucial, non-interfering internal standard for the precise quantification of Oseltamivir and its metabolites in biological matrices (e.g., plasma, serum) during bioanalytical studies.
• Metabolite Tracing & Pharmacokinetic Research: Enables accurate tracking and measurement of drug metabolism and absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical and clinical research.
• Method Development & Validation: Used to develop, optimize, and validate highly sensitive and specific analytical methods, ensuring regulatory compliance for drug testing.
• Deuterated Pharmaceutical Intermediate: Acts as a key synthon in the preparation of other deuterium-labeled compounds for advanced drug discovery programs.
• Quality Control & Reference Standard: Provides an authentic reference material for quality control laboratories to verify the identity and purity of Oseltamivir Acid in active pharmaceutical ingredient (API) manufacturing.

Basic Information

Product Name	Oseltamivir Acid-D3
CAS No.	1219172-31-2
Molecular Formula	C14H21D3N2O4
Molecular Weight	287.36 g/mol
Synonyms	(3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic Acid-d3; GS 4071-d3; Ro 64-0802-d3; Oseltamivir Carboxylate-d3; Oseltamivir-d3 Acid; [D3]-Oseltamivir Acid; Deuterated Oseltamivir Acid; Peramivir Impurity D-d3 (related compound)
EINECS	Contact for details

Quality Control

Our Oseltamivir Acid-D3 is manufactured under strict quality systems to ensure high chemical and isotopic purity, essential for reliable analytical results. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing purity, isotopic enrichment, and analytical data, supporting compliance with ICH Q2(R1) guidelines for analytical method validation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.