Description

Bml-275 CAS NO 1219168-18-9 is a high-purity, small molecule chemical compound primarily utilized as a potent and selective inhibitor of the BET (Bromodomain and Extra-Terminal) family of proteins. This compound matters for researchers and developers in the life sciences sector due to its critical role in modulating epigenetic pathways and gene expression. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on oncology, immunology, and inflammatory diseases.

Application

• Pharmaceutical Research & Development: As a key biochemical tool for studying BET bromodomain function and validating novel therapeutic targets in cancer and other diseases.
• Epigenetics & Gene Regulation Studies: Used in cellular and molecular biology assays to investigate chromatin remodeling and transcriptional control mechanisms.
• Preclinical Drug Discovery: Serves as a reference compound or positive control in high-throughput screening (HTS) and lead optimization programs for developing new BET inhibitors.
• Academic & Institutional Research: Employed in university and research institute laboratories for fundamental studies in cell signaling, proliferation, and differentiation.
• Biomarker & Diagnostic Development: Aids in understanding disease mechanisms to support the discovery of associated biomarkers.

Basic Information

Product Name	Bml-275
CAS No.	1219168-18-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BET Inhibitor BML-275; BML 275; BML275; (E)-N-(4-(2,4-Difluorophenoxy)-3-methoxyphenyl)-2-((4-(hydroxymethyl)piperidin-1-yl)methyl)but-2-enamide; 2-Butenamide, N-[4-(2,4-difluorophenoxy)-3-methoxyphenyl]-2-[[4-(hydroxymethyl)-1-piperidinyl]methyl]-, (2E)-
EINECS	Contact for details

Quality Control

Our Bml-275 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including purity assay and identity confirmation via advanced spectroscopic methods. Certificates of Analysis (COA) detailing all quality parameters are available upon request to support your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.