Description

2,3-Dihydro-5-Benzofuranacetic Acid-D2 Methyl Ester is a deuterated derivative of a key benzofuranacetic acid ester, serving as a valuable stable isotope-labeled building block. This compound is essential for advanced research and development, particularly in the fields of analytical chemistry and pharmacology, where precise molecular tracking is required. It is primarily sought after by pharmaceutical researchers, agrochemical developers, and contract research organizations (CROs) for use in metabolic studies, internal standards for mass spectrometry, and the synthesis of novel deuterated active pharmaceutical ingredients (APIs).

Application

• As a stable isotope-labeled internal standard for the accurate quantification of its non-deuterated counterpart in bioanalytical methods using LC-MS/MS.
• A critical deuterated synthetic intermediate in the research and development of novel pharmaceutical compounds, enhancing metabolic stability and enabling pharmacokinetic studies.
• Use in metabolic pathway tracing and mechanistic studies within pharmacological and agrochemical research.
• As a high-purity reference material for analytical method development and validation in quality control laboratories.
• Employed in deuterium labeling strategies to support drug discovery programs focused on improving drug efficacy and safety profiles.

Basic Information

Product Name	2,3-Dihydro-5-Benzofuranacetic Acid-D2 Methyl Ester
CAS No.	1219153-23-7
Molecular Formula	C₁₁H₁₀D₂O₃
Molecular Weight	194.23 g/mol
Synonyms	5-Benzofuranacetic acid, 2,3-dihydro-, methyl ester-2,2-d2; Methyl 2,3-dihydro-5-benzofuranacetate-d2; Methyl 2-(2,3-dihydrobenzofuran-5-yl)acetate-d2; Deuterated Methyl Dihydrobenzofuranacetate; [2,2-D2]-Methyl 2,3-dihydro-5-benzofuranacetate; Methyl 2-(2,3-dihydro-1-benzofuran-5-yl)acetate-2,2-d2
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-5-Benzofuranacetic Acid-D2 Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analysis, including NMR, HPLC, and mass spectrometry, to confirm chemical identity, isotopic enrichment (D2), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are properly sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D2, by MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.