Description

Deoxygalactonojirimycin-15N Hydrochloride is a nitrogen-15 labeled isotopologue of a potent and selective glycosidase inhibitor. This compound is a critical tool for advanced biochemical and pharmacological research, enabling precise metabolic and mechanistic studies through stable isotope tracing. It is primarily utilized by research scientists and process developers in the pharmaceutical and biotechnology sectors for drug discovery, enzyme mechanism elucidation, and metabolic pathway analysis.

Application

• Isotope-Labeled Biochemical Research: Serves as a crucial internal standard and tracer in mass spectrometry-based proteomic and metabolomic studies.
• Glycosidase Inhibition Studies: Used to investigate the mechanism of action and kinetics of α-galactosidases and related enzymes.
• Drug Discovery & Development: Employed in the research of potential therapeutics for lysosomal storage disorders like Fabry disease, Gaucher disease, and related glycosphingolipidoses.
• Metabolic Pathway Analysis: Facilitates the tracking and quantification of metabolic flux in cellular systems using NMR or LC-MS techniques.
• Pharmaceutical Reference Standard: Acts as a high-purity certified reference material (CRM) for quality control and analytical method development.
• Academic Research: Supports fundamental research in glycobiology, enzymology, and chemical biology at universities and research institutes.

Basic Information

Product Name	Deoxygalactonojirimycin-15N Hydrochloride
CAS No.	1219134-37-8
Molecular Formula	C7H1415NO4 • HCl
Molecular Weight	227.66 g/mol (for 15N isotopologue)
Synonyms	1-Deoxygalactonojirimycin-15N hydrochloride; DGal-15N HCl; 1,5-Dideoxy-1,5-imino-D-galactitol-15N hydrochloride; DGJ-15N HCl; (2R,3S,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol-15N hydrochloride; Migalastat-15N Impurity; AT2220-15N; Isofagomine-15N derivative; α-Galactosidase Inhibitor-15N
EINECS	Contact for details

Quality Control

Every batch of Deoxygalactonojirimycin-15N Hydrochloride is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity, isotopic enrichment, and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, isotopic purity, and residual solvent levels is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (15N)	≥ 98 atom %
Assay (Titration)	97.0% - 103.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.