Description

17-Phenyl Trinor Prostaglandin E2 Ethyl Amide is a synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural role in creating novel therapeutic agents targeting specific biological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in areas such as ophthalmology, dermatology, and metabolic disorders. The product is supplied to meet the stringent purity and consistency requirements of modern medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel prostaglandin-based drug candidates.
• Ophthalmic Research: Used in the development of new treatments for glaucoma and ocular hypertension.
• Dermatological Studies: Investigated for applications in wound healing, hair growth modulation, and skin inflammation models.
• Biochemical Research: Serves as a reference standard and a tool compound for studying prostaglandin receptor (EP) activity and signaling pathways.
• Metabolic Disorder Research: Explored in preclinical studies related to lipid metabolism and insulin sensitivity.
• Process Development: Used in scaling up and optimizing synthetic routes for prostaglandin analogs under GMP conditions.

Basic Information

Product Name	17-Phenyl Trinor Prostaglandin E2 Ethyl Amide
CAS No.	1219032-20-8
Molecular Formula	C25H35NO4
Molecular Weight	413.55 g/mol
Synonyms	17-Phenyl-trinor-PGE2 ethyl amide; PGE2 Ethyl Amide, 17-Phenyl-trinor-; AGN 192093; AGN-192093; 5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-4-phenyl-1-buten-1-yl]-5-oxocyclopentyl]-, ethylamide, (5Z)-; Ethyl (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-4-phenylbut-1-en-1-yl]-5-oxocyclopentyl]hept-5-enamide
EINECS	Contact for details

Quality Control

Our 17-Phenyl Trinor Prostaglandin E2 Ethyl Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.