Description

2-Fluoro-6-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value organoboron building block, specifically a pyridine-substituted pinacol boronic ester, essential for modern synthetic chemistry. Its core value lies in enabling Suzuki-Miyaura cross-coupling reactions, a pivotal method for constructing complex carbon-carbon bonds with high efficiency and selectivity. This compound is critically needed by R&D and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used to construct complex pyridine-based scaffolds for novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs, OFETs, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes and diagnostics.
• Catalyst Ligand Preparation: Utilized to synthesize novel nitrogen-containing ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs serving the global life sciences industry.

Basic Information

Item	Details
Product Name	2-Fluoro-6-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1218790-38-5
Molecular Formula	C13H19BFNO2
Molecular Weight	251.11 g/mol
Synonyms	2-Fluoro-6-methylpyridine-3-boronic acid pinacol ester; 3-Borono-2-fluoro-6-methylpyridine pinacol ester; (2-Fluoro-6-methylpyridin-3-yl)boronic acid pinacol ester; 2-Fluoro-6-methyl-3-pyridineboronic acid pinacol ester; 2-Fluoro-6-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 1218790-38-5; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluoro-6-methylpyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (¹H, ¹³C, ¹⁹F, ¹¹B), and GC/MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) and handle it in a controlled, low-humidity environment. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.