Description

2,6-Difluoro-3,5-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon and carbon-heteroatom bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of fluorinated heterocyclic compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where the difluoropyridine core and boronate groups allow for structural diversification.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs, OFETs, and conductive polymers.
• Suzuki-Miyaura Cross-Coupling: A versatile reagent for palladium-catalyzed coupling reactions to form biaryl and other conjugated systems with high efficiency and selectivity.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for imaging and diagnostic applications due to its functional handles.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis for creating diverse compound libraries in medicinal chemistry campaigns.

Basic Information

Product Name	2,6-Difluoro-3,5-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1218789-90-2
Molecular Formula	C19H28B2F2NO4
Molecular Weight	395.05 g/mol
Synonyms	3,5-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-2,6-Difluoropyridine; 2,6-Difluoropyridine-3,5-diyldiboronic Acid Bis(Pinacol) Ester; 2,6-Difluoro-3,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2,6-Difluoro-3,5-di(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3,5-Di(1,3,2-dioxaborinan-2-yl)-2,6-difluoropyridine Pinacol Ester; Pyridine, 2,6-difluoro-3,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3,5-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity building blocks for research and cGMP-intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.