Description

Albaconazole-D3 is a deuterated analog of the antifungal agent Albaconazole, specifically labeled with three deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring high accuracy and reproducibility in analytical methods. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers conducting pharmacokinetic, metabolic, and bioanalytical studies.

Application

• Internal standard for the LC-MS/MS quantification of Albaconazole in biological matrices (e.g., plasma, serum, tissue homogenates).
• Use in drug metabolism and pharmacokinetics (DMPK) studies to track the parent drug and its metabolites.
• Critical component in bioanalytical method development and validation for regulatory submissions.
• Supporting research in antifungal drug development and mechanism of action studies.
• Application in clinical trial sample analysis to ensure data integrity and compliance.
• Use in environmental or residue analysis where precise quantification of Albaconazole is required.

Basic Information

Product Name	Albaconazole-D3
CAS No.	1217825-34-7
Molecular Formula	C₂₃H₁₆D₃FN₄O₂
Molecular Weight	401.42 g/mol (approximate)
Synonyms	Albaconazole-d3; UNII-9F65R5WY6U (deuterated); 1-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(phenyl-d5)phenyl]-1H-1,2,4-triazol-5(4H)-one; Deuterated Albaconazole; Albaconazole Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Albaconazole-D3 CAS 1217825-34-7 is manufactured and analyzed under strict quality protocols. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically ≥98% by HPLC), isotopic enrichment (≥99 atom % D), and the absence of significant unlabeled impurities. Our quality system is designed to meet the rigorous standards of analytical and pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99 atom % D
Chemical Purity (by NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.