Description

3-Fluoro-2-Iodotoluenehydrochloride (Rs20010860) is a high-purity halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the precise introduction of fluorine and iodine substituents into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated and iodinated aromatic cores.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where halogenated toluenes confer specific biological activity and stability.
• Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive iodine moiety.
• Fluorination Studies: Used as a model compound in methodological development for selective fluorination and dehalogenation processes.
• Chemical Reference Standard: Employed in analytical laboratories for method development and calibration in chromatographic systems.

Basic Information

Product Name	3-Fluoro-2-Iodotoluenehydrochloride (Rs20010860)
CAS No.	1217806-37-5
Molecular Formula	C7H7ClFI
Molecular Weight	271.49 g/mol
Synonyms	1-Fluoro-2-iodo-3-methylbenzene hydrochloride; 2-Iodo-3-fluorotoluene hydrochloride; 3-Methyl-2-iodo-1-fluorobenzene hydrochloride; Toluene, 3-fluoro-2-iodo-, hydrochloride; Rs20010860; 3-F-2-I-Toluene·HCl
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Iodotoluenehydrochloride is manufactured under strict quality management protocols. We guarantee high chemical purity and lot-to-lot consistency, supported by comprehensive analytical testing including HPLC, NMR, and GC-MS. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.