Description

Danofloxacin-D3 is a deuterium-labeled internal standard of the veterinary fluoroquinolone antibiotic, Danofloxacin. This stable isotope-labeled compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analysis in complex biological matrices. It is a critical tool for researchers and quality control laboratories in the pharmaceutical and food safety sectors who require precise measurement of Danofloxacin residues.

Application

• Primary use as an Internal Standard for the quantitative LC-MS/MS analysis of Danofloxacin in biological samples (e.g., plasma, tissue, milk).
• Method development and validation for Danofloxacin residue testing in compliance with global veterinary drug monitoring programs.
• Pharmacokinetic and metabolism studies of Danofloxacin in livestock and poultry.
• Quality control and assurance in the manufacturing of veterinary pharmaceutical products.
• Research into the environmental fate and transport of fluoroquinolone antibiotics.
• Supporting regulatory submissions and forensic analysis requiring definitive identification and quantification.

Basic Information

Item	Detail
Product Name	Danofloxacin-D3
CAS No.	1217683-55-0
Molecular Formula	C19H17D3F2N3O3
Molecular Weight	Approx. 366.36 g/mol
Synonyms	Danofloxacin-d3; 1-Cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl]-5-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic-d3 acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-3-quinolinecarboxylic-d3 acid; ADVANTAGE-d3; (S)-(-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic-d3 acid (related structure); Deuterated Danofloxacin; Danofloxacin Internal Standard
EINECS	Contact for details

Quality Control

Our Danofloxacin-D3 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (chemical purity ≥98%, isotopic purity ≥99% D), assay by HPLC, and identification by NMR and MS. We adhere to relevant standards for high-purity reference materials to guarantee reliable and reproducible results in your critical assays.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the product label or COA. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99.0 atom % D
Chemical Purity	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.