Description

L-Dehydro Ascorbic Acid-13C6 is a stable isotope-labeled analog of dehydroascorbic acid, the oxidized form of vitamin C. This high-purity labeled compound is essential for precise quantitative analysis in metabolic and pharmacokinetic studies, providing unmatched accuracy as an internal standard. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories focused on redox biology, vitamin C metabolism, and advanced LC-MS/MS method development.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical, non-interfering internal standard for the accurate quantification of endogenous dehydroascorbic and ascorbic acid in biological matrices via LC-MS/MS.
• Metabolic Pathway Tracing: Used in in vitro and in vivo studies to elucidate the absorption, distribution, metabolism, and excretion (ADME) pathways of vitamin C and its redox cycle.
• Pharmaceutical R&D: Supports the development and validation of analytical methods for drug formulations and nutraceuticals containing vitamin C derivatives.
• Clinical Research: Enables precise measurement of oxidative stress biomarkers in plasma, serum, and tissue samples for clinical studies.
• Food & Nutraceutical Analysis: Applied in the quality control and stability testing of fortified foods and dietary supplements to monitor vitamin C degradation.
• Isotope Dilution Analysis (IDA): A key component in high-accuracy IDA protocols for certification of reference materials.

Basic Information

Product Name	L-Dehydro Ascorbic Acid-13C6
CAS No.	1217529-45-7
Molecular Formula	13C6H8O6
Molecular Weight	~180.10 g/mol (13C labeled)
Synonyms	Dehydro-L-ascorbic acid-13C6; (5R)-5-[(1S)-1,2-Dihydroxyethyl]-13C6-furan-2,3,4,5-tetrone; DHA-13C6; Oxidized L-ascorbic acid-13C6; Isotope-labeled dehydroascorbate; 13C6-Dehydroascorbic Acid; Vitamin C oxidation product-13C6
EINECS	Contact for details

Quality Control

Every batch of L-Dehydro Ascorbic Acid-13C6 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced spectroscopic and chromatographic techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific results for identity, purity, isotopic enrichment, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This compound is easily oxidized and moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For short-term use, keep the container in a desiccator at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.