Description

Nitrofurazone- 13 C, 15 N 2 is a stable isotope-labeled analog of the broad-spectrum antibacterial agent nitrofurazone. This compound is an essential internal standard and reference material for advanced analytical techniques, ensuring accurate quantification and method validation in research and quality control. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in pharmacokinetic studies, metabolic profiling, and residue analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in LC-MS/MS and GC-MS methods for analyzing nitrofurazone and its metabolites.
• Drug Metabolism and Pharmacokinetics (DMPK): Critical for tracing the absorption, distribution, metabolism, and excretion (ADME) pathways of nitrofurazone in preclinical and clinical studies.
• Veterinary and Agricultural Residue Testing: Enables precise detection and quantification of nitrofurazone residues in food products, animal tissues, and environmental samples to ensure regulatory compliance.
• Pharmaceutical Quality Control: Serves as a certified reference material (CRM) for assay validation, impurity profiling, and stability testing of nitrofurazone-containing formulations.
• Biomedical Research: Facilitates mechanistic studies on the antibacterial activity and potential toxicity of nitrofurazone using isotope tracing techniques.

Basic Information

Product Name	Nitrofurazone- 13 C, 15 N 2
CAS No.	1217220-85-3
Molecular Formula	C613C1H6N215N2O4
Molecular Weight	~201.1 g/mol (Contact for exact value)
Synonyms	5-Nitro-2-furaldehyde semicarbazone-13C,15N2; [13C,15N2]-Nitrofurazone; Nitrofurazone (13C,15N2); Isotopically Labeled Nitrofurazone; Furacin-13C,15N2; 5-Nitro-2-furfurylideneamino-13C,15N2 urea; (E)-5-Nitro-2-furaldehyde semicarbazone-13C,15N2
EINECS	Contact for details

Quality Control

Our stable isotope-labeled compounds are manufactured and verified under strict quality systems. Each batch of Nitrofurazone- 13 C, 15 N 2 is characterized using NMR (1H, 13C), high-resolution mass spectrometry (HRMS), and HPLC to confirm chemical structure, isotopic enrichment (typically >99 atom % 13C and >99 atom % 15N), and chemical purity. Certificates of Analysis (COA) detailing all analytical results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity (13C)	≥99 atom %
Isotopic Purity (15N)	≥99 atom %
Chemical Purity (HPLC)	≥98%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.