Description

Glycidamide-13C3 is a stable isotope-labeled analog of glycidamide, a key reactive metabolite of acrylamide. This compound is essential for advanced analytical research, providing the internal standard necessary for precise and accurate quantification in mass spectrometry. It is primarily used by researchers and quality control laboratories in the food safety, toxicology, and pharmaceutical industries to study metabolism, exposure assessment, and carcinogenicity.

Application

• Internal Standard for LC-MS/MS Analysis: Critical for the accurate quantification of glycidamide and related metabolites in complex biological matrices.
• Toxicology and Metabolic Pathway Studies: Used to trace and elucidate the metabolic fate of acrylamide in in vitro and in vivo systems.
• Food Safety and Exposure Assessment: Enables precise measurement of glycidamide-DNA adducts or hemoglobin adducts for biomonitoring human exposure from dietary sources.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Research: Supports studies investigating the absorption, distribution, metabolism, and excretion (ADME) of acrylamide.
• Method Development and Validation: Serves as a reference material for developing and validating robust analytical methods in regulatory and research settings.
• Quality Control in Reference Material Production: Used in the calibration and verification of assays for glycidamide in certified reference materials (CRMs).

Basic Information

Product Name	Glycidamide-13C3
CAS No.	1216449-31-8
Molecular Formula	C313C3H5NO2
Molecular Weight	92.05 g/mol (labeled)
Synonyms	2,3-Epoxypropanamide-13C3; (2-Oxiranyl)carboxamide-13C3; Glycidamide (13C3); 13C3-Glycidamide; Acrylamide epoxide-13C3; 3-Aminocarbonyloxirane-13C3; 2,3-Epoxypropionamide-13C3
EINECS	Contact for details

Quality Control

Our Glycidamide-13C3 is manufactured under strict quality systems to ensure high isotopic and chemical purity, essential for reliable analytical results. Each batch is thoroughly characterized using NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % 13C), chemical purity, and analytical data is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms
Isotopic Purity	≥99 atom % 13C
Chemical Purity (HPLC)	≥98%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.