Description

n-Desethyl Acetildenafil-D8 Dihydrochloride is a high-purity, deuterated reference standard and research chemical. This compound is critical for analytical and pharmaceutical research, providing a stable internal standard for precise quantification and metabolic studies. It is primarily utilized by analytical laboratories, pharmaceutical R&D departments, and contract research organizations (CROs) engaged in method development, quality control, and bioanalytical research.

Application

• Primary use as a deuterated internal standard for the accurate quantification of related compounds in complex matrices via LC-MS/MS.
• Critical component in pharmaceutical research and development for studying drug metabolism and pharmacokinetics (DMPK).
• Essential for analytical method development and validation in quality control laboratories to ensure specificity and accuracy.
• Used in forensic and anti-doping analysis for the identification and confirmation of specific substances.
• Supports reference material production for calibrating instruments and ensuring analytical consistency.
• Valuable for academic and institutional research in medicinal chemistry and pharmacology.

Basic Information

Product Name	n-Desethyl Acetildenafil-D8 Dihydrochloride
CAS No.	1215657-61-6
Molecular Formula	C23H22D8Cl2N6O4
Molecular Weight	Contact for details
Synonyms	Acetildenafil D8 Dihydrochloride; n-Desethyl Acetildenafil D8; Deuterated Acetildenafil Dihydrochloride; 2-[2-Ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one D8 Dihydrochloride; Acetildenafil-d8; Research Compound 1215657-61-6
EINECS	Contact for details

Quality Control

Our n-Desethyl Acetildenafil-D8 Dihydrochloride is manufactured under strict quality systems to ensure the highest standards of purity and consistency, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles. We adhere to relevant GMP and ISO guidelines for reference material production, ensuring traceability and reliability for your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.