Description

1-(6-Trifluoromethylpyridin-2-Yl)-1H-Imidzole is a high-value heterocyclic building block featuring a fused pyridine-imidazole core with a trifluoromethyl substituent. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where the CF3 group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel small-molecule drugs, particularly in kinase inhibitor and antiviral research.
• Agrochemical Active Ingredient Synthesis: Used in constructing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-donor ligands in coordination chemistry and catalytic systems.
• Material Science Research: Investigated as a building block for organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules at various scales.

Basic Information

Product Name	1-(6-Trifluoromethylpyridin-2-Yl)-1H-Imidzole
CAS No.	1215266-61-7
Molecular Formula	C9H6F3N3
Molecular Weight	213.16 g/mol
Synonyms	1-(6-(Trifluoromethyl)pyridin-2-yl)-1H-imidazole; 2-(1H-Imidazol-1-yl)-6-(trifluoromethyl)pyridine; 1H-Imidazole, 1-[6-(trifluoromethyl)-2-pyridinyl]-; 1-(6-Trifluoromethyl-2-pyridyl)imidazole; 1-(6-Trifluoromethylpyrid-2-yl)imidazole; 2-(Imidazol-1-yl)-6-trifluoromethylpyridine; 1-(6-(Trifluoromethyl)-2-pyridyl)-1H-imidazole
EINECS	Contact for details

Quality Control

Our 1-(6-Trifluoromethylpyridin-2-Yl)-1H-Imidzole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.