Description

4-(Chloromethyl)-1-Isopropoxy-2-(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethyl and chloromethyl functional groups, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes.
• Fluorinated Polymer Chemistry: Acts as a monomer or modifier to introduce fluorine into polymer chains, improving chemical resistance and thermal stability.
• Cross-Coupling Reactions: The chloromethyl group is a versatile handle for further functionalization via Suzuki, Heck, or other palladium-catalyzed couplings.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	4-(Chloromethyl)-1-Isopropoxy-2-(Trifluoromethyl)Benzene
CAS No.	1215118-94-7
Molecular Formula	C11H12ClF3O
Molecular Weight	252.66 g/mol
Synonyms	1-Isopropoxy-4-(chloromethyl)-2-(trifluoromethyl)benzene; 2-(Trifluoromethyl)-4-(chloromethyl)anisole, isopropyl derivative; 4-Chloromethyl-1-isopropoxy-2-trifluoromethylbenzene; 1-(Isopropoxy)-4-(chloromethyl)-2-(trifluoromethyl)benzene; α-Chloro-2-(trifluoromethyl)-4-isopropoxytoluene; Isopropyl 4-(chloromethyl)-3-(trifluoromethyl)phenyl ether; (4-Isopropoxy-3-(trifluoromethyl)phenyl)methyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-(Chloromethyl)-1-Isopropoxy-2-(Trifluoromethyl)Benzene is produced and tested under a strict quality management system. We ensure compliance with ISO 9001 standards and provide comprehensive analytical documentation. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and impurity profiles as per customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.