Description

2,3-Difluoro-4-(Trifluoromethyl)Pyridine is a high-value, multi-fluorinated heterocyclic building block essential for advanced chemical synthesis. Its unique structure, featuring both difluoro and trifluoromethyl substituents on the pyridine ring, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby modulating their physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of novel fluorinated polymers, liquid crystals, and electronic materials for specialized applications.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	2,3-Difluoro-4-(trifluoromethyl)pyridine
CAS No.	1215034-77-7
Molecular Formula	C6H2F5N
Molecular Weight	183.08 g/mol
Synonyms	4-(Trifluoromethyl)-2,3-difluoropyridine; 2,3-Difluoro-4-(trifluoromethyl)pyridine; 2,3-Difluoro-4-trifluoromethylpyridine; Pyridine, 2,3-difluoro-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-4-(Trifluoromethyl)Pyridine is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our quality control process includes advanced analytical techniques such as GC, HPLC, NMR, and MS to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.