Description

Methyl 6-Bromo-2-Fluoropyridine-3-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and the creation of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Used in fundamental research to explore new chemical reactions and develop novel synthetic methodologies.

Basic Information

Product Name	Methyl 6-Bromo-2-Fluoropyridine-3-Carboxylate
CAS No.	1214385-82-6
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	Methyl 6-bromo-2-fluoronicotinate; 6-Bromo-2-fluoropyridine-3-carboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 6-bromo-2-fluoro-, methyl ester; 2-Fluoro-6-bromonicotinic acid methyl ester; Methyl 2-fluoro-6-bromonicotinate; 6-Bromo-2-fluoro-3-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Bromo-2-Fluoropyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.