Description

1-Chloro-3-Methyl-5-(Trifluoromethyl)Benzene is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique structure, featuring chloro, methyl, and trifluoromethyl substituents, provides significant value in modulating the electronic and steric properties of target molecules. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a versatile precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its ability to fine-tune material properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Fluorine Chemistry: Acts as a valuable source of a fluorinated aromatic moiety in medicinal and materials chemistry research programs.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	1-Chloro-3-Methyl-5-(Trifluoromethyl)Benzene
CAS No.	1214384-22-1
Molecular Formula	C8H6ClF3
Molecular Weight	194.58 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)toluene; 5-Chloro-α,α,α-trifluoro-m-xylene; 1-Chloro-3-methyl-5-trifluoromethylbenzene; 3-Methyl-5-(trifluoromethyl)chlorobenzene; 3-Chloro-α,α,α-trifluoro-5-methyltoluene; m-Chloro-α,α,α-trifluoro-p-xylene; Benzene, 1-chloro-3-methyl-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 1-Chloro-3-Methyl-5-(Trifluoromethyl)Benzene is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for synthetic applications. Our quality commitment includes comprehensive identity, purity, and impurity profile verification. Certificates of Analysis (COA) with full traceability are provided for all commercial shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. The product is compatible with standard organic solvent containers.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.