Description

3-Bromo-2-Iodo-5-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, iodine, and a trifluoromethyl group on the pyridine ring, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the halogen and trifluoromethyl groups.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira cross-coupling reactions due to the reactive bromine and iodine atoms, enabling rapid diversification of molecular scaffolds.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Chemical Biology: Used as a probe or labeling reagent in biochemical research due to its distinct halogenated structure.

Basic Information

Item	Detail
Product Name	3-Bromo-2-Iodo-5-(Trifluoromethyl)Pyridine
CAS No.	1214383-73-9
Molecular Formula	C6H2BrF3IN
Molecular Weight	361.89 g/mol
Synonyms	3-Bromo-2-iodo-5-(trifluoromethyl)pyridine; 2-Iodo-3-bromo-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-bromo-2-iodopyridine; Pyridine, 3-bromo-2-iodo-5-(trifluoromethyl)-; 1214383-73-9
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Iodo-5-(Trifluoromethyl)Pyridine is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our commitment to quality supports compliance with the stringent requirements of pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.