Description

Ethyl 3-Bromo-6-Fluoropicolinate is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. This compound is valued for its unique halogenated picolinate structure, which enables precise molecular modifications in complex chemical pathways. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers due to its functional group versatility.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring bromo-fluoro substituted picolinate motifs.

Basic Information

Product Name	Ethyl 3-Bromo-6-Fluoropicolinate
CAS No.	1214377-16-8
Molecular Formula	C8H7BrFNO2
Molecular Weight	248.05 g/mol
Synonyms	Ethyl 3-bromo-6-fluoropyridine-2-carboxylate; 3-Bromo-6-fluoropicolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 3-bromo-6-fluoro-, ethyl ester; 6-Fluoro-3-bromopicolinic acid ethyl ester; Ethyl 3-bromo-6-fluoro-2-pyridinecarboxylate; 1214377-16-8; 3-Bromo-6-fluoro-2-pyridinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-6-Fluoropicolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.