Description

2-Fluoro-3-Iodo-5-Fluoropyridine is a high-purity, multi-halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine atoms, makes it a versatile intermediate for introducing specific halogen functionalities into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides where the halogenated pyridine core enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in cross-coupling reactions (e.g., Suzuki, Sonogashira) and organocatalysts.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers where halogen atoms tune electronic properties and intermolecular interactions.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to the reactivity of the iodine atom for further functionalization.

Basic Information

Product Name	2-Fluoro-3-Iodo-5-Fluoropyridine
CAS No.	1214377-11-3
Molecular Formula	C5H2F2IN
Molecular Weight	256.98 g/mol
Synonyms	3-Iodo-2,5-difluoropyridine; 2,5-Difluoro-3-iodopyridine; 5-Fluoro-3-iodo-2-fluoropyridine; Pyridine, 2-fluoro-3-iodo-5-fluoro-; 1214377-11-3; 2-Fluoro-3-iodo-5-fluoropyridine; 3-Iodo-2,5-difluoropyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodo-5-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.