Description

Ethyl 4-Fluoropicolinate is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Key synthetic intermediate in the research and development of novel pharmaceutical compounds.
• Building block for the synthesis of agrochemicals, including herbicides and fungicides.
• Precursor in the manufacture of liquid crystal materials and electronic chemicals.
• Versatile reagent for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Starting material for the preparation of fluorinated picolinamide derivatives with potential biological activity.
• Used in academic and industrial R&D for exploring structure-activity relationships (SAR) in drug discovery.

Basic Information

Product Name	Ethyl 4-Fluoropicolinate
CAS No.	1214376-12-1
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	Ethyl 4-fluoropyridine-2-carboxylate; 4-Fluoropicolinic Acid Ethyl Ester; 2-Pyridinecarboxylic acid, 4-fluoro-, ethyl ester; Ethyl 4-fluoro-2-pyridinecarboxylate; 4-Fluoro-2-pyridinecarboxylic acid ethyl ester; Ethyl 4-fluoropicolinate; 1214376-12-1
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoropicolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.