Description

3-Fluoro-2-Methoxy-Isonicotinic Acid Methyl Ester is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and methoxy substituents, makes it an essential intermediate for creating novel compounds with tailored biological and physical properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals for electronic applications.
• Chemical Biology Probes: Utilized to create fluorescent or bioactive probes for studying enzymatic activity and cellular processes.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Fluoro-2-Methoxy-Isonicotinic Acid Methyl Ester
CAS No.	1214375-56-0
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	Methyl 3-fluoro-2-methoxyisonicotinate; 3-Fluoro-2-methoxypyridine-4-carboxylic acid methyl ester; 2-Methoxy-3-fluoroisonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 3-fluoro-2-methoxy-, methyl ester; Isonicotinic acid, 3-fluoro-2-methoxy-, methyl ester; 1214375-56-0; Methyl 3-fluoro-2-methoxypyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Methoxy-Isonicotinic Acid Methyl Ester is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from atmospheric moisture and should be stored away from direct light sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.