Description

2-(4-Fluorophenyl)Isonicotinaldehyde is a high-purity fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a fluorinated biphenyl-like motif into their target structures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science applications.
• Fluorinated Liquid Crystal Development: Employed in the research and synthesis of advanced fluorinated organic compounds for electronic displays.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological studies in cross-coupling reactions and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis organizations (CSOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-(4-Fluorophenyl)Isonicotinaldehyde
CAS No.	1214368-14-5
Molecular Formula	C12H8FNO
Molecular Weight	201.20 g/mol
Synonyms	4-Fluoro-2-pyridin-4-ylbenzaldehyde; 2-(4-Fluorophenyl)-4-pyridinecarboxaldehyde; 4-Pyridinecarboxaldehyde, 2-(4-fluorophenyl)-; Isonicotinaldehyde, 2-(4-fluorophenyl)-; 2-(p-Fluorophenyl)isonicotinaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)Isonicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); it is recommended to handle and store under an inert atmosphere such as nitrogen or argon for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.