Description

1-(Difluoromethyl)-2,4-Dimethylbenzene is a specialized fluorinated aromatic compound, serving as a valuable building block in advanced organic synthesis. Its unique difluoromethyl group adjacent to a dimethyl-substituted benzene ring makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby modulating their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluoromethyl group can improve compound activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic semiconductors and liquid crystal molecules for electronic displays.
• Functional Material Development: Employed in creating specialty polymers, coatings, and additives that require specific dielectric or surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new fluorination methodologies and constructing complex molecular architectures.

Basic Information

Product Name	1-(Difluoromethyl)-2,4-Dimethylbenzene
CAS No.	1214367-22-2
Molecular Formula	C9H10F2
Molecular Weight	156.17 g/mol
Synonyms	2,4-Dimethyl-α,α-difluorotoluene; 2,4-Dimethylbenzylidene Difluoride; α,α-Difluoro-2,4-dimethyltoluene; 1-(Difluoromethyl)-2,4-dimethylbenzene; 2,4-Dimethyl-1-(difluoromethyl)benzene; (2,4-Dimethylphenyl)difluoromethane
EINECS	Contact for details

Quality Control

Our 1-(Difluoromethyl)-2,4-Dimethylbenzene is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. We provide Certificates of Analysis (COA) with detailed specifications for all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.