Description

3-Fluoro-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs contribute to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Fluoro-6-(trifluoromethyl)pyridine-2-carboxylic acid
CAS No.	1214365-86-2
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-fluoro-6-(trifluoromethyl)-; 3-Fluoro-6-(trifluoromethyl)picolinic acid; 6-(Trifluoromethyl)-3-fluoropyridine-2-carboxylic acid; 3-Fluoro-6-trifluoromethylpyridine-2-carboxylic acid; 3-Fluoro-6-trifluoromethyl-2-pyridinecarboxylic acid; 1214365-86-2; 3-Fluoro-6-(trifluoromethyl)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment is designed to meet the exacting standards of pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.