Description

3-(3-Fluorophenyl)-5-Methoxypyridine is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a fluorine atom and a methoxy group on a bipyridine-like scaffold, enabling precise modulation of electronic and steric properties in target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for constructing sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive compounds for OLEDs.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Scale-Up: Available for contract research organizations (CROs) and CDMOs for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	3-(3-Fluorophenyl)-5-Methoxypyridine
CAS No.	1214364-48-3
Molecular Formula	C₁₂H₁₀FNO
Molecular Weight	203.21 g/mol
Synonyms	5-Methoxy-3-(3-fluorophenyl)pyridine; 3-(3-Fluorophenyl)-5-methoxypyridine; 3-Fluoro-3'-methoxy-3,4'-bipyridine; 5-Methoxy-3-(m-fluorophenyl)pyridine; 3-(3-Fluorophenyl)-5-pyridinol methyl ether; 3-(m-Fluorophenyl)-5-methoxypyridine; 3-Fluoro-5'-methoxy-1,1'-biphenyl-3-carbonitrile (incorrect but sometimes indexed); 1214364-48-3
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Fluorophenyl)-5-Methoxypyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot. We support development and commercial projects with specifications that can meet GMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time matches reference standard
Identification (IR)	Spectrum conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.