Description

3-Bromo-2-Difluoromethoxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and fluorinated structure makes it an essential intermediate for developing novel active ingredients with enhanced properties. This compound is primarily targeted at the pharmaceutical and agrochemical industries for the research and production of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the research and manufacturing of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms improve metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for synthesizing specialty chemicals, liquid crystals, and advanced polymers with specific electronic or surface properties.
• Chemical Biology & Proteomics: Employed as a molecular probe or labeling agent in biochemical research due to its reactive bromo and stable trifluoromethyl groups.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies and CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Bromo-2-Difluoromethoxy-5-(Trifluoromethyl)Pyridine
CAS No.	1214363-95-7
Molecular Formula	C7H3BrF5NO
Molecular Weight	291.99 g/mol
Synonyms	3-Bromo-2-(difluoromethoxy)-5-(trifluoromethyl)pyridine; 2-(Difluoromethoxy)-3-bromo-5-(trifluoromethyl)pyridine; Pyridine, 3-bromo-2-(difluoromethoxy)-5-(trifluoromethyl)-; 1214363-95-7; 3-Bromo-2-difluoromethoxy-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated pyridine intermediates. Each batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.