Description

Ethyl 3-Bromo-6-(Trifluoromethyl)Pyridine-2-Carboxylate is a high-purity, multi-functional pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering a unique trifluoromethyl and bromo substitution pattern for targeted structural modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and liquid crystals with tailored electronic properties.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution for constructing complex heterocyclic systems.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis projects and library generation for high-throughput screening.

Basic Information

Product Name	Ethyl 3-Bromo-6-(Trifluoromethyl)Pyridine-2-Carboxylate
CAS No.	1214363-72-0
Molecular Formula	C9H7BrF3NO2
Molecular Weight	298.06 g/mol
Synonyms	Ethyl 3-bromo-6-(trifluoromethyl)pyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 3-bromo-6-(trifluoromethyl)-, ethyl ester; 3-Bromo-6-(trifluoromethyl)picolinic acid ethyl ester; Ethyl 3-bromo-6-trifluoromethylpicolinate; 3-Bromo-6-(trifluoromethyl)-2-pyridinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 3-Bromo-6-(Trifluoromethyl)Pyridine-2-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We operate under a quality system aligned with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.