Description

Ethyl 5,6-Difluoropicolinate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce difluorinated pyridine motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a building block for fluorinated polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CMOs for client-specific research and scale-up projects.

Basic Information

Product Name	Ethyl 5,6-Difluoropicolinate
CAS No.	1214363-04-8
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	5,6-Difluoropyridine-2-carboxylic acid ethyl ester; Ethyl 5,6-difluoropyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 5,6-difluoro-, ethyl ester; 5,6-Difluoropicolinic acid ethyl ester; Ethyl 5,6-difluoro-2-pyridinecarboxylate; 1214363-04-8; 5,6-Difluoro-2-pyridinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5,6-Difluoropicolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Handle and store in accordance with good laboratory and industrial safety practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.