Description

4-Chloro-2-Methoxy-1-(Trifluoromethyl)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique trifluoromethyl and chloro-methoxy substitution pattern, which imparts significant electronic and steric properties crucial for developing active pharmaceutical ingredients and agrochemicals. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electronic chemicals used in display technologies, leveraging its aromatic core and halogen substituents.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in catalytic systems.
• Polymer & Resin Modifier: Incorporated to introduce specific functional groups that alter the thermal or chemical resistance of high-performance polymers.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex colorants and functional dyes for specialized applications.

Basic Information

Product Name	4-Chloro-2-Methoxy-1-(Trifluoromethyl)Benzene
CAS No.	1214362-99-8
Molecular Formula	C8H6ClF3O
Molecular Weight	210.58 g/mol
Synonyms	1-Chloro-4-methoxy-2-(trifluoromethyl)benzene; 2-Methoxy-4-chloro-α,α,α-trifluorotoluene; 4-Chloro-2-methoxybenzotrifluoride; 4-Chloro-α,α,α-trifluoro-2-methoxytoluene; 2-Methoxy-4-chlorobenzotrifluoride; 4-Chloro-2-(trifluoromethyl)anisole; 2-Trifluoromethyl-4-chloroanisole; 4-Chloro-2-methoxy-1-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methoxy-1-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.