Description

2-Fluoro-4-Methyl-5-Phenylpyridine is a high-value fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and phenyl substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides that require fluorinated pyridine cores for enhanced bioactivity and stability.
• Material Science Research: Used in the creation of specialty chemicals, liquid crystals, and organic electronic materials due to its aromatic and fluorine-containing structure.
• Chemical Biology Probes: Serves as a scaffold for designing molecular probes and tags used in biochemical assays and diagnostic development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated heterocycles.

Basic Information

Product Name	2-Fluoro-4-Methyl-5-Phenylpyridine
CAS No.	1214362-19-2
Molecular Formula	C₁₂H₁₀FN
Molecular Weight	187.21 g/mol
Synonyms	5-Phenyl-2-fluoro-4-picoline; 2-Fluoro-4-methyl-5-phenylpyridine; 4-Methyl-2-fluoro-5-phenylpyridine; 5-Phenyl-2-fluoro-4-methylpyridine; 2-Fluoro-5-phenyl-4-picoline; 4-Methyl-5-phenyl-2-fluoropyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Methyl-5-Phenylpyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.