Description

2-Fluoro-3-Methyl-5-Phenylpyridine is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both fluorine and phenyl substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and other functional materials requiring specific electronic properties.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological processes and protein interactions.
• Catalyst Ligand Development: Acts as a building block for synthesizing novel ligand systems in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trials.

Basic Information

Product Name	2-Fluoro-3-Methyl-5-Phenylpyridine
CAS No.	1214362-13-6
Molecular Formula	C₁₂H₁₀FN
Molecular Weight	187.21 g/mol
Synonyms	5-Phenyl-2-fluoro-3-picoline; 3-Methyl-5-phenyl-2-fluoropyridine; 2-Fluoro-3-methyl-5-phenylpyridine; 2-Fluoro-3-picoline, 5-phenyl-; 1214362-13-6; 5-Phenyl-2-fluoro-3-methylpyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methyl-5-Phenylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment supports applications requiring high-purity intermediates for research and regulated production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.