Description

2-(Difluoromethyl)-4-Fluoro-1-(Trifluoromethyl) Benzene is a high-value, multi-fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring both difluoromethyl and trifluoromethyl groups, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a fluorinated core component in the synthesis of high-performance liquid crystals for display technologies.
• Organic Electronics: Employed in the development of novel organic semiconductors and charge-transport materials due to its electron-withdrawing properties.
• Advanced Polymer Chemistry: Acts as a monomer or modifier to incorporate fluorine into specialty polymers, improving chemical resistance and thermal stability.
• Fluorinated Dye & Pigment Intermediate: Used to create novel fluorinated dyes and pigments with unique optical properties.

Basic Information

Product Name	2-(Difluoromethyl)-4-Fluoro-1-(Trifluoromethyl) Benzene
CAS No.	1214358-19-6
Molecular Formula	C9H4F6
Molecular Weight	226.12 g/mol
Synonyms	1-(Difluoromethyl)-2-fluoro-4-(trifluoromethyl)benzene; 2-Fluoro-α,α-difluoro-4-(trifluoromethyl)toluene; 4-Fluoro-2-(difluoromethyl)benzotrifluoride; 2-Fluoro-α,α,α,4-tetrafluorotoluene; Benzene, 2-(difluoromethyl)-4-fluoro-1-(trifluoromethyl)-; α,α-Difluoro-2-fluoro-4-(trifluoromethyl)toluene
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethyl)-4-Fluoro-1-(Trifluoromethyl) Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.