Description

3-Amino-2,5-Difluoropyridine Hcl is a high-purity, halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical structure, which introduces both fluorine atoms and an amino group onto the pyridine ring, enabling precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and stability.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	3-Amino-2,5-Difluoropyridine Hcl
CAS No.	1214349-97-9
Molecular Formula	C5H5ClF2N2
Molecular Weight	166.56 g/mol
Synonyms	3-Amino-2,5-difluoropyridine hydrochloride; 2,5-Difluoropyridin-3-amine hydrochloride; 3-Amino-2,5-difluoropyridine monohydrochloride; 2,5-Difluoro-3-pyridinamine hydrochloride; 1214349-97-9; 3-Pyridinamine, 2,5-difluoro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 3-Amino-2,5-Difluoropyridine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.