Description

2-Chloro-3-(Trifluoromethyl)Benzenesulphonylchloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and halogenated aromatic structure. This compound matters for its critical role as a key building block in the synthesis of advanced agrochemicals and pharmaceuticals, enabling the introduction of the sulfonamide moiety. It is primarily needed by R&D chemists and process development scientists in the fine chemical, crop protection, and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A pivotal precursor for the synthesis of modern herbicides, fungicides, and insecticides, leveraging the sulfonamide group for bioactivity.
• Pharmaceutical Building Block: Used in medicinal chemistry research for the development of new drug candidates, particularly those targeting enzymes where sulfonamides act as inhibitors.
• Dyestuff and Pigment Synthesis: Serves as a reactant in the production of specialized dyes and organic pigments, contributing to color fastness and specific properties.
• Polymer Modification: Employed to introduce sulfonyl chloride functional groups into polymer chains, altering material characteristics like solubility and reactivity.
• Cross-coupling Reactions: The chloro and trifluoromethyl groups make it a suitable substrate for various palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: Utilized in academic and industrial labs for exploring new synthetic pathways and creating novel chemical entities for various applications.

Basic Information

Product Name	2-Chloro-3-(Trifluoromethyl)Benzenesulphonylchloride
CAS No.	1214346-10-7
Molecular Formula	C7H3Cl2F3O2S
Molecular Weight	278.06 g/mol
Synonyms	2-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride; 2-Chloro-alpha,alpha,α-trifluoro-m-toluenesulfonyl chloride; 3-Chloro-2-(trifluoromethyl)benzenesulfonyl chloride; 1-Chloro-2-(chlorosulfonyl)-6-(trifluoromethyl)benzene; Benzenesulfonyl chloride, 2-chloro-3-(trifluoromethyl)-; m-Toluenesulfonyl chloride, 2-chloro-alpha,alpha,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(Trifluoromethyl)Benzenesulphonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under a dry, inert atmosphere (e.g., nitrogen) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0 - 102.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.