Description

Methyl 2-Bromo-5-Fluoropyridine-3-Carboxylate is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound is specifically engineered to serve as a key intermediate in the development of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Facilitates exploratory chemistry in university and corporate laboratories for discovering new chemical entities and reaction methodologies.

Basic Information

Product Name	Methyl 2-Bromo-5-Fluoropyridine-3-Carboxylate
CAS No.	1214336-94-3
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	3-Pyridinecarboxylic acid, 2-bromo-5-fluoro-, methyl ester; Methyl 2-bromo-5-fluoronicotinate; 2-Bromo-5-fluoropyridine-3-carboxylic acid methyl ester; Methyl 2-bromo-5-fluoro-3-pyridinecarboxylate; 2-Bromo-5-fluoro-3-(methoxycarbonyl)pyridine; 1214336-94-3; MFCD30566633
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Bromo-5-Fluoropyridine-3-Carboxylate is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) with full analytical data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.