Description

3,6-Difluoropicolinonitrile is a high-value fluorinated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both nitrile and fluorine substituents, makes it an essential building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Used to create sophisticated ligands for transition metal catalysis and organocatalysts in asymmetric synthesis.
• Material Science Research: Intermediate for synthesizing fluorinated organic semiconductors, liquid crystals, and other functional materials.
• Chemical Biology Probes: Serves as a starting point for creating fluorescent tags and molecular probes for biological imaging and diagnostics.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up.

Basic Information

Product Name	3,6-Difluoropicolinonitrile
CAS No.	1214332-12-3
Molecular Formula	C6H2F2N2
Molecular Weight	140.09 g/mol
Synonyms	2-Cyano-3,6-difluoropyridine; 3,6-Difluoro-2-pyridinecarbonitrile; 3,6-Difluoropyridine-2-carbonitrile; 2-Pyridinecarbonitrile, 3,6-difluoro-; Picolinonitrile, 3,6-difluoro-
EINECS	Contact for details

Quality Control

Our 3,6-Difluoropicolinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients with full traceability and documentation to meet the stringent requirements of pharmaceutical and agrochemical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.