Description

2,6-Difluoro-3-methoxypyridine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy substituents, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery, particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where the difluoropyridine core contributes to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	2,6-Difluoro-3-methoxypyridine
CAS No.	1214331-52-8
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	3-Methoxy-2,6-difluoropyridine; 2,6-Difluoro-3-methoxypyridine; Pyridine, 2,6-difluoro-3-methoxy-; 1214331-52-8
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-3-methoxypyridine is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by HPLC, GC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed and stored in a desiccator if long-term storage is required to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.