Description

Methyl 5,6-Difluoropicolinate is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its role as a key intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the difluoro substitution pattern is essential for modulating biological activity and physicochemical properties. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used as a building block for developing new-generation herbicides and fungicides with enhanced efficacy.
• Ligand & Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated organic semiconductors and liquid crystal materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production.

Basic Information

Product Name	Methyl 5,6-Difluoropicolinate
CAS No.	1214324-54-5
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	Methyl 5,6-difluoropyridine-2-carboxylate; 5,6-Difluoropicolinic acid methyl ester; 2-Pyridinecarboxylic acid, 5,6-difluoro-, methyl ester; Methyl 5,6-difluoro-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5,6-Difluoropicolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.