Description

(R)-1-(5-Fluoropyridin-3-yl)ethanamine is a chiral amine building block of significant interest in advanced organic synthesis. Its core value lies in its stereochemistry and the fluoropyridine moiety, which are critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, antiviral agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and receptor interactions.
• Material Science Research: Investigated as a monomer or functionalization agent for creating specialty polymers with unique electronic or surface properties.

Basic Information

Product Name	(R)-1-(5-Fluoropyridin-3-yl)ethanamine
CAS No.	1212854-34-6
Molecular Formula	C7H9FN2
Molecular Weight	140.16 g/mol
Synonyms	(R)-1-(5-Fluoro-3-pyridinyl)ethanamine; (R)-1-(5-Fluoropyridin-3-yl)ethylamine; (R)-α-Methyl-5-fluoronicotinylamine; (R)-5-Fluoro-3-(1-aminoethyl)pyridine; (R)-5-Fluoro-3-(1-aminoethyl)pyridine; (R)-1-(5-Fluoro-3-pyridyl)ethan-1-amine; (R)-5-Fluoronicotinamide derivative intermediate
EINECS	Contact for details

Quality Control

Our (R)-1-(5-Fluoropyridin-3-yl)ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.