Description

4-Bromo-3-Chloro-5-Fluoropyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogen substitution pattern, which enables precise molecular modifications in complex chemical architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides requiring specific halogenated heterocycles.
• Material Science Precursor: Serves as a building block for creating functionalized ligands, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the reactive bromo substituent.
• Nucleophilic Aromatic Substitution: The chloro and fluoro groups provide sites for selective displacement with various nucleophiles.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-Bromo-3-Chloro-5-Fluoropyridine
CAS No.	1211590-18-9
Molecular Formula	C5H2BrClFN
Molecular Weight	210.43 g/mol
Synonyms	3-Chloro-5-fluoro-4-bromopyridine; 5-Fluoro-4-bromo-3-chloropyridine; 4-Bromo-3-chloro-5-fluoropyridine; Pyridine, 4-bromo-3-chloro-5-fluoro-; 1211590-18-9; BCFP; 3-Chloro-4-bromo-5-fluoropyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-5-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.