Description

2-Fluoro-5-Methoxypyridine-4-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and methoxy substituents on the pyridine core, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Fluoro-5-Methoxypyridine-4-Carboxylic Acid
CAS No.	1211587-56-2
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	4-Pyridinecarboxylic acid, 2-fluoro-5-methoxy-; 5-Methoxy-2-fluoropyridine-4-carboxylic acid; 2-Fluoro-5-methoxypicolinic acid; 2-Fluoro-5-methoxyisonicotinic acid; 1211587-56-2; 2-Fluoro-5-methoxy-4-pyridinecarboxylic acid; 2-F-5-MeO-Pic-OH
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methoxypyridine-4-Carboxylic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.